News for Healthier Living

How Mimicry and Manipulation Enable Bone Metastases

Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses.

September 3, 2025

September 8 2025

• MSU Researchers Address Gap in Substance Use Disorder Treatment
• Study Led by Roswell Park's Dr. Sai Yendamuri Finds GLP-1 Receptor Agonists Improve Lung Cancer Outcomes
• Meet Wolfram Goessling, New Chair of the Yale Department of Internal Medicine
• Mayo Clinic Q and A: Living Kidney Donation May Be Option for Those with Type 2 Diabetes
• UNC Physicians Develop Fast Treatment to Ease Depression in Pregnant and Postpartum Women
• Using AI to Identify Personalized Heart, Blood Pressure Rates Could Help Reduce ICU Deaths
• IU Scientists Reprogram Cancer-Protecting Regulatory T Cells to Fight Tumors
• Nicotine Pouches May Offer Path to Reduced Tobacco Harm, Rutgers Study Finds
• Blood Test Could Streamline Early Alzheimer's Detection
• First-Ever Clinical Trial Demonstrates Safety, Molecular Readout and Promise of Pre- and Post-Surgery Immunotherapy Combination for Patients with Operable Mesothelioma
• FDA Expands Use of Vonvendi for Von Willebrand Disease
• Pre-Conception Radiation Exposure From CT Scans Increases Risk for Miscarriage and Birth Defects
• Ryan White HIV/AIDS Program Cuts Could Trigger a Substantial Spike in Infections by 2030
• Radioactive Contamination Suspected in Recalled Frozen Shrimp
• HHS Withdraws Report Linking Alcohol to Higher Cancer Risks
• Salmonella Outbreak Tied to Metabolic Meals Sickens 16, CDC Warns
• Johns Hopkins Medicine Patient Loses Nearly 100 Pounds with Help of Care Team
• Moffitt Develops First Genetically Engineered Cancer Model in Naked Mole Rats
• Automated Smoking Interventions Offered to Parents through Pediatric Primary Care May Curb Their Tobacco Habits
• Cancer Cells Can Use Backup Routes to Fuel Their Growth
• New Pill Lowers Stubborn BP In Kidney Patients
• Space Travel Accelerates Cellular Aging, Researchers Say
• Kids with High BP May Face Risk of Early Heart Disease Death as Adults
• FDA Warns of Juice Recall Linked to Potential Foodborne Illness
• AI Aids Seniors In Reading, Reporting Blood Pressure At Home
• Severe Pregnancy Nausea Causes Many To Rethink Motherhood, Study Finds

September 7 2025

• Substance Use During Pregnancy Can Harm a Fetus, Experts Warn

September 6 2025

• Cats Get Dementia Just Like People, Making Them a Potential Research Tool

September 5 2025

• After Early-Life Stress, Astrocytes Affect Behaviour
• Hitting One Target Could Cripple Brain Tumors in Two Critical Ways
• How Can We Age Gracefully?
• Skin Protein Found to Use Physical Tension to Control Tissue Growth
• Mitochondrial Antioxidant Found to Drive Breast Cancer Metastasis
• Virtual Reality Games Help Kids in the Clinic, but What Should Parents Know About Safe Use at Home?
• These Genetic Insights Into Rheumatoid Arthritis Could Help Design Better Treatments
• Cedars-Sinai Conference: IBD's Impact on Women's Health
• MD Anderson Research Highlights for September 5, 2025
• Mastering Recovery: How One Incision Got a Golfer Back to Augusta
• Coral-Inspired Pill Offers a New Window Into the Hidden World of the Gut
• D-CARE Study Finds Caregiver Satisfaction Higher with Dementia Care Programs Than Usual Care
• LSD May Ease Anxiety Symptoms for Months, Study Finds
• New Ebola Outbreak Declared in Congo
• Raw Cat Food Linked to H5N1 Virus After Infected Cat Is Euthanized
• Pocket Ultrasound Reduces Hospital Stays for Patients with Shortness of Breath
• Folks Skipping Salt Substitutes — Even Those With High Blood Pressure
• Blood Pressure-Related Kidney Deaths Increased Dramatically Over Last Quarter-Century
• Music Soothes Savage Motion Sickness, Experiment Shows
• Scrolling On The Toilet Increases Risk Of Hemorrhoids, Study Says
• Self-Medicating With Weed Might Make Things Worse
• Breast Milk Timing Crucial For Babies' Sleep, Researchers Say

September 4 2025

• MSU Study Finds Accessible Wireless Ultrasounds Are Accurate
• Making Progress Toward Equitable Food Systems in the Mississippi Delta
• UI Health Performs First Islet Cell Transplant with Lantidra
• Single Hair Strand Could Provide Biomarker for ALS, Mount Sinai Study Finds
• Basu Completes First Phase of Groundbreaking Cardiac Visualization Project
• In Extensive Sequencing Study, Scientists Find Few Links Between Cancer and Microbiome
• PCOM Georgia Study Finds Settings Influence Participation in Children With Cerebral Palsy
• Mapping Thermal Risks: New Insights Into Safe Diazotization of 2-ANDSA
• Cancer Treatment Creates Special Bond for Johns Hopkins Children's Center Patient and His Sister
• Dietary Changes Could Provide a Therapeutic Avenue for Brain Cancer
• Digital Science Investigation Shows Millions of Taxpayers' Money Has Been Awarded to Researchers Associated with Fictitious Network
• ASTRO to Showcase Advances in Radiation Medicine and Cancer Research in 2025 Annual Meeting Press Program
• New Gel May Help Prevent Hair Loss During Chemotherapy, Early Research Finds
• Researchers Reveal Potential Molecular Link Between Air Pollutants and Increased Risk of Lewy Body Dementia
• Advanced Prostate Cancer Cases Rising as Fewer Men Are Screened, New Report Says
• Florida Plans to End All Vaccine Mandates
• The Brain-Heart Connection: Mayo Clinic Expert Explains Powerful Tie That Works Both Ways
• Spaceflight Accelerates Human Stem Cell Aging, UC San Diego Researchers Find
• How Stress and Social Struggles Fuel America's Obesity Crisis
• Study Shows How Smoking Drives Pancreatic Cancer
• Life Expectancy Is Plateauing, Won't Reach 100, Researchers Say
• Community Hospitals Failing To Transfer Injury Patients To Better Facilities
• Sugar Substitutes Could Be Bad For Brain Aging, Study Argues
• Daily Pill Might Help People With Stubborn High Blood Pressure
• Single-Dose Penicillin Effective Against Early Syphilis
• Saliva Might Keep Fruit Juice From Rotting Teeth, Study Says
• New AI Tool Addresses Accuracy and Fairness in Data to Improve Health Algorithms
• Healthy -- or Unhealthy -- Childhood Habits Could Shape Adult Habits
• New Study Links Grain Foods to Healthier Diet Patterns, Metabolic Health and Everyday Accessibility
• What to Know About the Medical Keto Diet for Epilepsy
• IRB Barcelona Researchers Uncover a New Strategy to Tackle Obesity by Activating Brown Fat

September 3 2025

• Rutgers and RWJBarnabas Health Study Finds Pocket Ultrasound Reduces Hospital Stays for Patients with Shortness of Breath
• Are Probiotics Worth the Cost to Prevent Infection After a Colon Removal Surgery?
• New Clinical Trial to Test Sensory Prostheses for People with Upper-Limb Loss
• The Medical Minute: I'm Cold, Bald, Flat and Bloated. What's Wrong? Blame Menopause
• Breaking Down Barriers to Support People Living with Obesity
• A New Paradigm for Understanding Social Cognition
• Delta-8 THC Use Highest Where Marijuana Is Illegal, Study Finds
• Every College Student Should Carry Naloxone - Expert Advice from RWJBarnabas Health
• How Mimicry and Manipulation Enable Bone Metastases
• 'Timekeeper' Shapes Body's Infection Defenses, UTSW Study Finds
• Researchers Identify Single Antibody Behind Life-Threatening Reaction to Common Blood Thinner
• Not So Sweet: Some Sugar Substitutes Linked to Faster Cognitive Decline
• Helping Your College-Bound Kids Head Back To School
• DermaRite Expands Recall of Creams and Sanitizers Over Infection Risk
• Wegovy Linked To Lower Heart Risks Than Similar Drugs, Study Shows
• Taylor Fresh Foods Issues Recall of Salad Kits Sold at Kroger, Walmart
• Sip Smarter: Apple Juice Effects on Oral Health Are Short-Lived, Study Suggests
• Mount Sinai Study Discovers Potential Link Between Stress and Type 2 Diabetes
• Children with Sickle Cell Disease Face Higher Risk of Dental Issues, Yet Many Don't Receive Needed Care
• Multicenter Study Shows U.S. Hospitals Vary Greatly in How They Define Blood Culture Contamination
• New Research Reveals a Link Between Excessive Alcohol and Fatty Liver Disease
• Experts Highlight Science-Driven Approaches to Addiction
• Kathy Coleman Commits Additional $3.5 Million to Fuel the Future of Clinical Trials at University Hospitals Seidman Cancer Center
• It's Still Tough to Find a Key Anti-Opioid Treatment at U.S. Pharmacies
• One Dose of RSV Vaccine May Shield Older People for Two Seasons
• Chatbots Give Users 'Inconsistent' Info on Suicide, Study Finds
• Could Diabetes Drug Metformin Change Metal Levels in Your Blood?
• Study Casts Doubt on Use of Beta Blockers Post-Heart Attack, Especially for Women
• Tip Sheet: What Cancer Patients Need to Know About Tumor Markers, a New Cancer Genetics Atlas -- and Educational Programs for Students and Teachers
• Obtaining Prefrontal Cortex Biopsies During Deep Brain Stimulation Adds No Risk to Procedure
• The Nature of Cancer
• Liver-Directed Treatment Is Associated with Improved Survival and Increased Response to Immune Checkpoint Blockade in Metastatic Uveal Melanoma: Results From a Retrospective Multicenter Trial
• Machine Learning Modeling Identifies Hypertrophic Cardiomyopathy Subtypes with Genetic Signature
• Hyperosmolarity Promotes Macrophage Pyroptosis by Driving the Glycolytic Reprogramming of Corneal Epithelial Cells in Dry Eye Disease
• FERM Domain-Containing Protein FRMD6 Activates the mTOR Signaling Pathway and Promotes Lung Cancer Progression
• Dihydroartemisinin Increased the Abundance of Akkermansia Muciniphila by YAP1 Depression That Sensitizes Hepatocellular Carcinoma to Anti-PD-1 Immunotherapy
• Evaluating Chatbot Accuracy in the Fast-Changing Blood Cancer Field
• Q&A: How Pediatric Cancer Care Is Changing--and What's Next
• "Most-Favored Nation" Drug Pricing Strategy May Backfire, New Research Warns
• Cleveland Clinic Finds Most Men Say Exercise Positively Impacts Their Mental Health, Confidence, and Sex Drive, but Nearly 1 in 3 Still Skip It

September 2 2025

• Researchers Find Medicaid Is Crucial to Access Treatment for Opioid Addiction
• Shampoo-Like Gel Could Help Chemo Patients Keep Their Hair
• Back-to-School Anxiety: Easing Into a New Environment
• Advances in Ultrasound Drive Gains in Prenatal Heart Defect Detection, But Regional Gaps Remain
• New Charts for Artery Stiffness Could Flag Heart Risk Long Before Symptoms
• Johns Hopkins Investigators Create New Urine-based Test to ID Prostate Cancers
• FDA Approves Subcutaneous Leqembi for Treatment of Early Alzheimer Disease
• Molecule Shows Promise for MASH, Endometriosis, and Other Chronic Diseases
• Bristol PhD Researcher on Personal Mission to Help Detect Breast Cancer Early Invents Temperature-Sensing Patch
• Little-Known Heat Health Risk: Kidney Stones
• Quantum Brilliance, ORNL Pioneer Quantum-Classical Hybrid Computing
• Few Women Participate in Studies for Common Cardiac Conditions
• California Program Successfully Scales Emergency Department Addiction Treatment Statewide
• Jim O’Neill Steps in as Acting CDC Chief Amid Firing, Resignations
• CVS, Walgreens Limit COVID Vaccines in Some States as Rules Shift
• Gordon Ramsay Reveals Skin Cancer Diagnosis, Urges Folks To Use Sunscreen
• A Prelude to a Cure: How One Man's Courage is Redefining the Fight Against Prostate Cancer
• Shorter, Less Intense Radiation-Chemo Regimen Effective for HPV-Linked Oropharyngeal Cancer, Mayo Study Shows
• Illinois Researchers Unlock New Insights Into Granular Hydrogels for Biomedical Applications
• Immune Molecule Long Tied to Inflammation May Benefit the Aging Brain
• New ACS Prostate Cancer Statistics Report: Late-Stage Incidence Rates Continue to Increase Rapidly as Mortality Declines Slow
• What Retina Specialists Want You to Know About Protecting Vision As You Age
• Heart Failure Strikes Black Americans Almost 14 Years Earlier Than White Americans
• New Law Curbed 'Surprise' Medical Bills For Patients, Cut Out-Of-Pocket Costs
• Most Don't Know Prostate Cancer Can Be a Silent Killer, Poll Finds
• ADHD Drugs Often Prescribed Too Early To Preschoolers
• Feel the Beat: Music Might Help Regulate Blood Pressure
• 'Reborn Again': Blind Bride-To-Be Thriving After Triple-Organ Transplant
• New Genetic Biomarker Flags Aggressive Brain Tumors
• Scientists Discover the Brain Signaling That Sets Parkinson's Disease Apart From Essential Tremor
• Pioneering Strategy May Keep Breast Cancer From Coming Back
• Immunosuppressive Tumor Microenvironment Contributes to Tumor Progression in Diffuse Large B-Cell Lymphoma Upon Anti-CD19 Chimeric Antigen Receptor T Therapy
• Host Protection Against Omicron BA.2.2 Sublineages by Prior Vaccination in Spring 2022 COVID-19 Outbreak in Shanghai
• Control of Lupus Activity During Pregnancy via the Engagement of Igg Sialylation: Novel Crosstalk Between IgG Sialylation and pDC Functions
• Blinded by Childhood Cancer, Bride-to-Be Gets New Chance at Life with Rare Triple-Organ Transplant at Northwestern Medicine

September 1 2025

• Personalized Risk Messages Fail to Boost Colorectal Cancer Screening Participation
• Report Highlights the Value of Editorial Oversight and Peer Review in Clinical Trial Reporting
• Study Sheds Light on How Pediatric Brain Tumors Grow
• New Artificial Intelligence Model Accurately Identifies Which Atrial Fibrillation Patients Need Blood Thinners to Prevent Stroke
• Testosterone's Hidden Role in Aging, Heart, and Mind
• Penile Implant Satisfaction Drops in Prostate Cancer Patients on Hormonal Treatment
• Mapping Fluid Reservoir Dynamics in Scleral Lens Wear
• Genetic Analysis Links Prostate Cancer to Urothelial Carcinoma Risk
• MicroRNA Panels Pave New Path for Precision Prostate Cancer Care
• Nurses Offer Insights Into Caring for ICU Patients With Intellectual Developmental Disabilities

August 31 2025

• Toxic Algae in Lakes Can Kill Pets Within Minutes, Expert Warns
• Saying YES to Careers in Oncology

August 30 2025

• Labor Day Mission: Build Social Ties Through Live Events
• One Shot of RSV Vaccine Effective Against Hospitalization in Older Adults for Two Seasons
• Beta Blockers, the Standard Treatment After a Heart Attack, May Offer No Benefit for Heart Attack Patients and Women Can Have Worse Outcomes

August 29 2025

• SLU Study Highlights Pickleball's Safety for Overweight Players, Ideal for Weight Control
• Uncovering Links Between Depression and Hypertension in African Populations
• New CT-Based Model Enhances Accuracy in Maize Endosperm Segmentation
• Should I Get My Child Circumcised?
• Polarization Around Vaccine Hesitancy Was 12 Times Greater Than Past Outbreaks, Study Finds
• Examining the Impact of Treating and Preventing Obesity to Prevent Obesity-Related Conditions
• At Least 95 Sickened in Salmonella Outbreak Linked To Recalled Eggs
• CDC Scales Back Foodborne Illness Tracking
• Louisiana Oysters Linked to Deadly Vibrio Outbreak, Officials Warn
• UCLA Scientists Develop Off-the-Shelf Immunotherapy for Metastatic Kidney Cancer
• Mount Sinai-Duke University Study Identifies DNA Variants That Increase Testosterone Production in PCOS Patients
• Shingles Vaccine Might Protect Against Heart Attack, Stroke
• Hormone Therapy For Menopause Might Provide Memory Boost
• Good Sleep, Eating Right Tied To Better Mental Well-Being Among Young Adults
• Skipping Breakfast? Beware Broken Bones, Study Says
• Plant-Based Diet Protects Against Multiple Chronic Illnesses
• Common Pain Meds Could Be Contributing To Antibiotic Resistance
• Drones and Deep Learning Boost Soybean Breeding with 3D Canopy Insights
• Glycan Codes in the Kidney: The Role of Glycosylation in Disease

August 28 2025

• Cells 'vomit' waste to promote healing, mouse study reveals
• Breast Reconstruction Preferences Among African American Women - New Data From Plastic and Reconstructive Surgery
• Unveiling the Molecular Mechanism of Vision Using Ultrafast X-ray Pulses
• Roswell Park Study Reveals New Clues to Pancreatic Cancer Spread -- and a Possible Way to Stop It
• 'Young' Immune Cells Could Treat Alzheimer's, Aging Symptoms
• Back to School: How Screen Time Affects Children's Developing Brains
• Illinois Analysis Aims to Ease GI Symptoms for Cancer Patients
• New Research Involving CHLA Neurologists Explores Prevention Strategies for a Severe Neurological Complication Associated with the Flu
• Researchers Train AI to Diagnose Heart Failure in Rural Patients Using Low-Tech Electrocardiograms
• Vertigo-Free Pirouettes: It's All in the Dancer's Head
• Student Research Explores Mental Health for Law Enforcement
• Removing Barriers for Young People With Disabilities
• Mount Sinai Researchers Use AI and Lab Tests to Predict Genetic Disease Risk
• CDC Director Susan Monarez Fired Less Than a Month Into Role
• FDA Approves Updated COVID Vaccines, but Fewer People Will Be Eligible
• School Connection May Protect Teens From Depression Linked To Bullying
• New Blood Test for ALS Detects Early Signs Years Before Symptoms Appear
• Cleveland Clinic Research Finds Injectable Obesity Medications Associated with Reduced Risk for Eye Inflammation
• The Brain's Activity at Rest May Provide Clues to Alzheimer's Disease Progression, Diagnosis
• Study Identifies Key Features of Cancer Cell Response and Resistance to Treatment
• Data Science Uncovers Patterns in Health Service Use Linked to Child Mortality
• A Sense Of Purpose Can Protect Brain Health In Aging
• Fatty Foods Might Contribute To Childhood Asthma
• CPR In Space? Best Method Identified, Researchers Say
• Middle-Aged Folks At Risk For Irregular Heartbeat, Especially If They Don't Work Out
• GLP-1 Drugs Are Good For Climate Change, Heart Study Says
• Why Cheap Cigarettes From Other States Are a Costly Problem for New York City
• Diet, Exercise Protect Liver Health From Alcohol Damage, Study Says
• People Who Skip Breakfast and Eat Late Dinners May Have a Higher Risk of Osteoporosis
• Why Implants Fail
• Fall Allergy Symptoms Are Similar to Spring and Summer - and Can Hit as Hard
• First Global Guidelines for Pregnancy and Inflammatory Bowel Disease Developed
• Cracking the KRAS Code: New Hope for Pancreatic Cancer Patients

August 27 2025

• A New Computational Tool Maps Genome Change, Helping Researchers See DNA in 3D
• New Editorial Explores the Double-Edged Sword of AI Scribes in Health Care
• A Stunning First Look at the Viruses Inside Us
• Light Pills Could Transform Understanding of How the Gut Controls the Body
• New Research Reveals Longevity Gains Slowing, Life Expectancy of 100 Unlikely
• AI Analysis of Colonoscopy Improves Assessment of Crohn's Disease
• UWF Receives $32.5 Million Triumph Grant to Advance Cybersecurity and Computational Research
• One in Seven Bariatric Surgery Patients Turn to New Weight Loss Drugs
• Rewiring Addiction With Designer Proteins
• How to Respond to an Opioid Overdose: Expert Advice from RWJBarnabas Health
• Many Patients with Advanced Cancer Feel Their Treatment Is Not Aligned with Their Personal Care Goals
• First Enzyme-Targeting Drug Reverses Liver Damage in MASH
• Stroke Risk Highest Among Native Hawaiian, Pacific Islander People
• Hormone Therapy Type Matters for Memory Performance After Menopause
• Children's Hospital of Philadelphia Researchers Link Dietary Fats to More Severe Form of Asthma
• Be it Feast or Famine, Orangutans Adapt With Flexible Diets
• New GLP-1 Pill Helps People Lose 23 Pounds in Study
• CDC's Anti-Smoking Ads Set to End After 13 Years
• Spring Into Health: UniSA's Healthy Choices Program Drives Real Change
• UCLA Scientists Uncover Brain Network Controlling Stress and Social Behavior in Mice
• Housing Aid Linked to Lower Medical Financial Hardship Among U.S. Renters with Cancer
• Half of Critically Injured Patients First Seen at Level III or Non-Trauma Centers are Never Transferred to Necessary Higher-Level Care
• Test Detects Brain Cancers in Cerebrospinal Fluid with High Accuracy
• Next-Generation 'Molecular Scissors' May Offer Hope for Chronic Hepatitis B Sufferers
• Drowning In Chaos? A New Mindset Can Protect Against Depression, Stress
• Heart Patients Urged To Seek Vaccination For Common Infectious Diseases
• More Women In Study Reveals Heart Risk For Men
• Child Gun Wounds More Common In Poor Neighborhoods
• Breath Test For Diabetes Under Development
• Talk Therapy Alters Brain Structure, MRI Scans Show
• Smart Biosensors That Bend, Stretch, and Sense
• The Clinical Impact of Tricuspid Regurgitation in Patients with a Biatrial Orthotopic Heart Transplant
• Aldolase B Attenuates Clear Cell Renal Cell Carcinoma Progression by Inhibiting CtBP2
• Venous Thromboembolism in Children with Acute Lymphoblastic Leukemia in China: A Report From the Chinese Children's Cancer Group-ALL-2015
• Potential Unreliability of ALK Variant Allele Frequency in the Efficacy Prediction of Targeted Therapy in NSCLC

August 26 2025

• Cognitive Behavioural Therapy Can Alter Brain Structure and Boost Grey Matter Volume, Study Shows
• Mount Sinai Scientists Identify Three Potent Human Antibodies Against Mpox, Paving the Way for New Protective Therapies
• Beyond Hospital Walls: Cedars-Sinai's Community Health Workers
• The Experts' Guide to Safely Pumping, Storing And Thawing Breast Milk
• Statistical Dietary Exposure Tools Help Managers Protect Health
• U.S. Resident Diagnosed With Rare Screwworm Parasite After Travel
• Pig Lung Transplanted Into Man for 9 Days in Groundbreaking Study
• Common Painkillers Linked to Antibiotic Resistance
• Roswell Park Leads Largest-Ever Genomic Study of Triple-Negative Breast Cancer in African American Women
• New Hope for Osteoarthritis: Upstate Offers Gentle Radiation Therapy
• Overweight Older Adults Face Lower Risk of Death After Major Surgery
• Advancing Therapies for Pulmonary Fibrosis
• Genetic Study Yields Personalized Therapeutics for a Rare Skin Disorder
• Study Ties Genetics and Common Anticoagulant to Risk of Intracranial Hemorrhage
• How HIV Uses T Cells to Hide in the Gut
• Future Dentists Don White Coats, Embrace Mission to Serve Our Borderplex
• Many Cancer Patients Say Doctors Aren't Honoring Their Treatment Desires
• Firearm-Related Suicides Increasing Among Senior Women
• Mediterranean Diet Can Protect Against Type 2 Diabetes
• 2 In 3 Women Have A Lifestyle Risk Factor For Birth Defects
• It Takes About A Year To Get Epilepsy Under Control For Most, Study Says
• U.S. Justice Department Subpoenas Health Records of Young Transgender Patients
• Reimagining Vision: Redefining Eye Treatment for a Healthier Future
• Tribological Behavior of Tool-Workpiece Interface During Milling of Ultra-High Strength Steel Under Different Cooling Conditions
• Stable Blood Pressure Does Not Free Everyone of Cardiovascular Risk, New Study Finds
• A Novel Variant in the GJB6 Gene in a Large Chinese Family with a Unique Phenotype of Clouston Syndrome
• lncR-GAS5 Upregulates the Splicing Factor SRSF10 to Impair Endothelial Autophagy, Leading to Atherogenesis