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News for Healthier Living

Cleveland Clinic Research Links Tumor Bacteria to Immunotherapy Resistance in Head and Neck Cancer

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others. Two new studies, published simultaneously in Nature Cancer, reveal that elevated levels of bacteria in the tumor microenvironment suppress immune response, driving resistance to immunotherapy in patients with head and neck squamous cell carcinoma.

January 2, 2026


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