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News for Healthier Living

Sharpening an Essential Tool for Biotechnology

Scientists at the Department of Energy's Oak Ridge National Laboratory showed that more than 93 percent of possible E. coli CRISPR-Cas9 guide RNAs -- molecules that direct the gene-editing CRISPR tool to the right spot in DNA -- work as intended, far higher than researchers expected. They also discovered why a small number of guides fail and developed a simple way to repair them.

August 26, 2026


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