1525 Superior Avenue, Suite 200
Newport Beach, CA 92663
Phone (949) 650-0506
Fax (949) 999-8126

Receive our newsletter
  Home  
  Our Team  
  Patient Info  
  Contact Us  

News for Healthier Living

Psycho-Cardiovascular Interaction Network Links Mental Health and Heart Disease

A new review proposes the psycho-cardiovascular interaction network (PCIN), a framework that links psychological and psychiatric factors with cardiovascular health and disease. The review integrates epidemiological evidence, system-level mechanisms, and molecular signaling pathways to explain how depression, anxiety, chronic stress, and other mental health conditions may contribute to cardiovascular disease (CVD), and vice versa. It focuses on five representative pathways--brain-derived neurotrophic factor (BDNF), prokineticin (PROK)/prokineticin receptor (PKR), mitogen-activated protein kinase (MAPK), 5-hydroxytryptamine (5-HT)/5-HT2A receptor (5-HT2A-R), and NOD-like receptor protein 3 (NLRP3) inflammasome signaling--and discusses integrated prevention and treatment strategies.

September 28, 2026


October 12 2026

October 11 2026

October 10 2026

October 9 2026

October 8 2026

October 7 2026

October 6 2026

October 5 2026

October 2 2026

October 1 2026

September 30 2026

September 29 2026

September 28 2026